To identify new gene and protein markers of metastasis, the MetaBre partners will analyse samples of breast tumours and metastases, with due care of ethical aspects, as well as established breast cancer cell lines.

MetaBre aims to discover new metastatic interactions but also studies genes and molecules that are already suspected of involvement in metastasis. This builds on previous work of the partners and will enhance understanding of the role of these molecules in metastasis in breast cancer, as well as identifying new therapies and diagnostic methods against these targets.

MetaBre has research activities aimed at:

MetaBre will use state-of-the-art Affymetrix™ chips for gene profiling and will develop novel in-vitro and in-vivo models for validation of molecular targets and screening of therapeutic molecules.